Tanishing Deyv — to'liq cast

Eddie Murphy

as Dave / Captain

Elizabeth Banks

as Gina Morrison

Gabrielle Union

as No. 3 - Cultural Officer

Scott Caan

as Dooley

Ed Helms

as No. 2 - Second-in-Command

Kevin Hart

as No. 17

Mike O'Malley

as Knox

Pat Kilbane

as No. 4 - Security Officer

Judah Friedlander

as Engineer

Marc Blucas

as Mark

Jim Turner

as Doctor

Austyn Myers

as Josh Morrison

Adam Tomei

as No. 35

Brian Huskey

as Lieutenant Right Arm

Shawn Christian

as Lieutenant Left Arm

Rob Moran

as ER Doctor

Jane Bradbury

as No. 81 - Female Crew

Brad Wilson

as Lieutenant Right Leg

Miguel A. Núñez Jr.

as Burly Crew Member

John Gatins

as Air Traffic Controller